IGF2BP2 Polyclonal Antibody

Background:
RNA-binding factor that recruits target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation (By similarity). Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. Binds to beta-actin/ACTB and MYC transcripts.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Immunology, Signaling transduction

Synonyms:
Hepatocellular carcinoma autoantigen p62, IF2B2, IGF 2 mRNA binding protein 2, IGF II mRNA binding protein 2, IGF-II mRNA-binding protein 2, IGF2 mRNA-binding protein 2, Igf2bp2, IMP 2, IMP-2, IMP2, Insulin like growth factor 2 mRNA binding protein 2, Insulin-like growth factor 2 mRNA-binding protein 2, OTTHUMP00000082606, OTTHUMP00000082607, OTTHUMP00000082608, p62, VICKZ 2, VICKZ family member 2, VICKZ2

Immunogen: Recombinant human Insulin-like growth factor 2 mRNA-binding protein 2 protein

Swissprot: Q9Y6M1

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 2 mg/mL
Dilution: IHC 1:50-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.