IGF2BP3 Polyclonal Antibody

Background:
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.

Research Area: Cancer, Epigenetics and Nuclear Signaling

Synonyms:
IGF2BP3, CT98, IMP-3, IMP3, KOC, KOC1, VICKZ3

Immunogen: Recombinant fusion protein of human IGF2BP3 (NP_006538.2).

Swissprot: O00425
Gene ID: 10643

Calculated MW: 21 kDa/63 kDa
Observed MW: 70 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.