IGF2R polyclonal, anti-human, mouse

Background:
This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

Synonyms: MPR1, MPRI, CD222, CIMPR, M6P-R

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human IGF2R

Gene Symbol: IGF2R

Gene ID: 3482

Swiss prot: P11717

Calculated MW: 274kDa

Recommended dilution:
WB 1:200-1000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.