E2F-4 polyclonal, anti-human, mouse, rat
€470.00
In stock
SKU
AC-AP73505
Background:
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.
Other Names:
E2F4; Transcription factor E2F4; E2F-4
Antigen Type: synthetic peptide
Antigen Type: E2F4
Gene ID: 1874
Primary Accession: Q16254
Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC- 3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.
Other Names:
E2F4; Transcription factor E2F4; E2F-4
Antigen Type: synthetic peptide
Antigen Type: E2F4
Gene ID: 1874
Primary Accession: Q16254
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