IgG (Immunoglobulin Gamma Heavy Chain) (B Cell Marker) (clone SPM556 ), anti-human

Background:
Recognizes a protein of 75kDa, identified as γ heavy chain of human immunoglobulins. It does not cross-react with α (IgA), μ (IgM), ε (IgE), or δ (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin�s lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

Other Names:
Ig gamma-1 chain C region, IGHG1

Gene Name: IGHG1 {ECO:0000303|PubMed:11340299, ECO:0000303|Ref.13}
Primary Accession: P01857
Other Accession: 3500 (IGHG1), 3501 (IGHG2), 3502 (IGHG3), 3503 (IGHG4), 510635,P01859,P01860,P01861