IGSF10 Polyclonal Antibody

Background:
Ig (immunoglobulin) superfamily members exhibit functional characteristics including immune responses, growth factor signaling and cell adhesion. IGSF10 (immunoglobulin superfamily, member 10), also known as Calvaria mechanical force protein 608 (CMF608), is a 2,623 amino acid secreted protein that contains an N-terminal signal peptide, six leucine-rich repeats (LRRs), and 12 immunoglobulin-like repeats. IGSF10 exists as multiple alternatively spliced isoforms, and is expressed in bone. Specifically, expression of IGSF10 is limited to mesenchymal osteochondroprogenitors with fibroblast-like morphology, where it is thought to be involved in the maintenance of the osteochondroprogenitor cells pool and its down-regulation precedes terminal differentiation.

Research Area: Cancer, Cell Biology, Developmental Biology, Immunology, Signal Transduction

Synonyms:
6530405F15Rik, 9030224D03, AA409708, AA536958, Adlican2, AI414626, Calvaria mechanical force protein 608, CMF608, IGS10, IgSF10, Immunoglobulin superfamily member 10

Immunogen: Recombinant protein of human IGSF10

Swissprot: Q6WRI0
Gene Accession: BC031063

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.7 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-99935