IGSF3 polyclonal, anti-human
€388.00
In stock
SKU
BS70861
Background:
IGSF3 (immunoglobulin superfamily, member 3), also known as V8 or EWI-3, is a 1,214 amino acid protein. Widely expressed with predominant expression in kidney, placenta and lung, IGSF3 localizes to the membrane and contains an N-terminal signal peptide, eight immunoglobulin (Ig) domains and a transmembrane segment. IGSF3 exhibits strong sequence and structural similarity to CD101 (32% identity), a leukocyte surface protein with seven Ig domains that is believed to play a role in T-cell activation. Despite the structural similarities between IGSF3 and CD101, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in an immune function.
Alternative Name:
Immunoglobulin superfamily member 3, IgSF3, EWI-3, EWI3, KIAA0466
Application Dilution: WB: 1:500 - 1:2000
Specificity: IGSF3 polyclonal antibody detects endogenous levels of IGSF3 protein.
Immunogen:
Recombinant Protein of human IGSF3.
MW: ~ 135 kDa
Swis Prot.: O75054
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
IGSF3 (immunoglobulin superfamily, member 3), also known as V8 or EWI-3, is a 1,214 amino acid protein. Widely expressed with predominant expression in kidney, placenta and lung, IGSF3 localizes to the membrane and contains an N-terminal signal peptide, eight immunoglobulin (Ig) domains and a transmembrane segment. IGSF3 exhibits strong sequence and structural similarity to CD101 (32% identity), a leukocyte surface protein with seven Ig domains that is believed to play a role in T-cell activation. Despite the structural similarities between IGSF3 and CD101, IGSF3 is not expressed in peripheral blood lymphocytes and does not appear to participate in an immune function.
Alternative Name:
Immunoglobulin superfamily member 3, IgSF3, EWI-3, EWI3, KIAA0466
Application Dilution: WB: 1:500 - 1:2000
Specificity: IGSF3 polyclonal antibody detects endogenous levels of IGSF3 protein.
Immunogen:
Recombinant Protein of human IGSF3.
MW: ~ 135 kDa
Swis Prot.: O75054
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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