Ikaros 3 Polyclonal Antibody

Background:
IKAROS family zinc finger 3(IKZF3) Homo sapiens This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012],

Alternative Names:
IKZF3, ZNFN1A3, Zinc finger protein Aiolos, Ikaros family zinc finger protein 3

Immunogen: The antiserum was produced against synthesized peptide derived from human IKZF3. AA range:361-410

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 62

GeneID: IKZF3

Storage: -20°C/1 year

NOTE: For Research Use Only