IkB-α polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.

Synonyms: IKBA, MAD-3, NFKBI

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human NFKBIA

Gene Symbol: IkB-α

Gene ID: 4792

Swiss prot: P25963

Calculated MW: 36kDa

Recommended dilution:
IHC 1:15-50

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.