IκB α polyclonal, anti-human, rat

Background:
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines.

Synonyms: IKBA, MAD-3, NFKBI

Cellular Location: Cytoplasm Nucleus

Immunogen:
Recombinant Protein

Gene Symbol: IκB α

Gene ID: 4792

Swiss prot: P25963

Calculated MW: 40kDa

Recommended dilution:
WB 1:2000-5000, IHC 1:200-500,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.