IKB epsilon polyclonal, anti-human

Background:
 ,On the basis of both functional and structural considerations, members of the IκB family of proteins can be divided into four groups. The first of these groups, IκB-α, includes the avian protein pp40 and the mammalian MAD-3, both of which inhibit binding of p50-p65 NFkB complex or Rel protein to their cognate binding sites but do not inhibit the binding of p50 homodimer to κB sites, suggesting that the IκB-α family binds to the p65 subunit of p50-p65 heterocomplex through ankyrin repeats. The second member of the IκB family is represented by a protein designated IκB-β. The third group of IκB proteins is represented by IκB-γ, which is identical in sequence with the C-terminal domain of the p110 precursor of NFkB p50 and is expressed predominantly in lymphoid cells. An additional IκB family member, IκB-ε, has several phosphorylated forms and is primarily found complexed with Rel A and/or c-Rel. ,

Alternative Name:
NF-kappa-BIE, IkB-E, IkB-epsilon, IkappaBepsilon, I kappa B epsilon, I-kappa-B-epsilon, IkappaBepsilon, IkB E, IkB-E, IkB-epsilon, IKBE, IKBE, MGC72568, NF kappa B inhibitor epsilon, NF kappa BIE, NF-kappa-B inhibitor epsilon, NF-kappa-BIE, NFkappa BIE, NFkappaB inhibitor epsilon, NFKBIE, Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor epsilon, OTTHUMP00000016522, Slc35b2, solute carrier family 35, member B2,

Application Dilution:
WB:1:500-1:1,000
IHC:1:50-1:200

Specificity: IKB epsilon polyclonal antibody detects endogenous levels of IKB epsilon protein.

Immunogen:
Recombinant protein

MW: 45 kDa

Swiss-Prot: O00221(Human)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.