IKBA polyclonal, anti-human, mouse

Background:
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

Synonyms: ACAS2, ACECS, ACS, ACSA, dJ1161H23.1

Cellular Location: Nucleus

Immunogen:
A synthetic peptide of human IKBA

Gene Symbol: IKBA

Gene ID: 18035

Swiss prot: Q9Z1E3

Calculated MW: 32kDa

Recommended dilution:
WB 1:3000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.