IkBalpha (clone 6A055), anti-human antibody
€325.00
In stock
SKU
AC-ABV10239-100
Catalog Number: AC-ABV10239-100
Size: 100 µg
Host: Mouse IgG
Applications: WB, IHC, IP
Datasheet
Request Information
Size: 100 µg
Host: Mouse IgG
Applications: WB, IHC, IP
Datasheet
Request Information
Background:
NF-kB is silenced in the cytoplasm by an inhibitory protein, IkB. IkB proteins are phosphorylated by IkB kinase complex consisting of at least three proteins, IKK1/α, IKK2/β, and IKK3/g. External stimuli such TNF-α or other cytokines results in phosphorylation and degradation of IkB releasing NF-kB dimers. NF-kB dimer subsequently translocates to the nucleus and activates target genes. Six members of IkB family members have been identified. One of the first gene induced following NF-kB activation is IkBα.
Other Names:
IkappaBalpha , MAD3, MAD-3, IKBA, NFKBI, IKB-alpha, I-kappa-B-alpha
Primary Accession: P25963
Gene Name: NFKBIA
Gene ID: 4792
Concentration (mg/ml): 0.25 mg/ml
NF-kB is silenced in the cytoplasm by an inhibitory protein, IkB. IkB proteins are phosphorylated by IkB kinase complex consisting of at least three proteins, IKK1/α, IKK2/β, and IKK3/g. External stimuli such TNF-α or other cytokines results in phosphorylation and degradation of IkB releasing NF-kB dimers. NF-kB dimer subsequently translocates to the nucleus and activates target genes. Six members of IkB family members have been identified. One of the first gene induced following NF-kB activation is IkBα.
Other Names:
IkappaBalpha , MAD3, MAD-3, IKBA, NFKBI, IKB-alpha, I-kappa-B-alpha
Primary Accession: P25963
Gene Name: NFKBIA
Gene ID: 4792
Concentration (mg/ml): 0.25 mg/ml
| Is Featured? | No |
|---|
Write Your Own Review