IKBKAP polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms: DYS, ELP1, FD, IKAP, IKI3, TOT1

Cellular Location: Cytoplasm Nucleus

Immunogen:
Recombinant protein of human IKBKAP

Gene Symbol: IKBKAP

Gene ID: 8518

Swiss prot: O95163

Calculated MW: 150kDa

Recommended dilution:
WB 1:1000-4000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.