IKBKE polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6488
Background:
The functional IKK complex contains three subunits, IKKα, IKKβ and IKKγ (also designated NEMO), and each appear to make essential contributions to IκB phosphorylation. IKK-i is a serine/threonine kinase that shares homology with IKKα and IKKβ. IKK-i is primarily expressed in immune cells and is induced by lipopolysaccharide and by proinflammatory cytokines including TNFα, IL-1 and IL-6. Overexpression of IKK-i was shown to result in phosphorylation of IκBα on Ser32 and Ser36, and in NFκB activation, suggesting that IKK-i may act as an IκB kinase in the immune system.
Alternative Name:
I kappa B kinase epsilon, I-kappa-B kinase epsilon, IkBKE, IKBKE protein, IKK E, IKK i, IKK related kinase epsilon, IKK-E, IKK-epsilon, IKK-i, IKKE, IKKE, IKKepsilon, IKKI, Inducible I kappa B kinase, Inducible I kappa-B kinase, inducible IkappaB kinase, Inhibitor of kappa light polypeptide gene enhancer in B cells kinase epsilon, Inhibitor of nuclear factor kappa B kinase subunit epsilon, Inhibitor of nuclear factor kappa-B kinase subunit epsilon, KIAA0151, MGC125294, MGC125295, MGC125297
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200, IP 1:50 - 1:100
Specificity: IKBKE polyclonal antibody detects endogenous levels of IKBKE protein.
Immunogen:
Recombinant full length Human IKBKE.
MW: ~ 80 kDa
Swis Prot.: Q14164
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The functional IKK complex contains three subunits, IKKα, IKKβ and IKKγ (also designated NEMO), and each appear to make essential contributions to IκB phosphorylation. IKK-i is a serine/threonine kinase that shares homology with IKKα and IKKβ. IKK-i is primarily expressed in immune cells and is induced by lipopolysaccharide and by proinflammatory cytokines including TNFα, IL-1 and IL-6. Overexpression of IKK-i was shown to result in phosphorylation of IκBα on Ser32 and Ser36, and in NFκB activation, suggesting that IKK-i may act as an IκB kinase in the immune system.
Alternative Name:
I kappa B kinase epsilon, I-kappa-B kinase epsilon, IkBKE, IKBKE protein, IKK E, IKK i, IKK related kinase epsilon, IKK-E, IKK-epsilon, IKK-i, IKKE, IKKE, IKKepsilon, IKKI, Inducible I kappa B kinase, Inducible I kappa-B kinase, inducible IkappaB kinase, Inhibitor of kappa light polypeptide gene enhancer in B cells kinase epsilon, Inhibitor of nuclear factor kappa B kinase subunit epsilon, Inhibitor of nuclear factor kappa-B kinase subunit epsilon, KIAA0151, MGC125294, MGC125295, MGC125297
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200, IP 1:50 - 1:100
Specificity: IKBKE polyclonal antibody detects endogenous levels of IKBKE protein.
Immunogen:
Recombinant full length Human IKBKE.
MW: ~ 80 kDa
Swis Prot.: Q14164
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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