IKBKG antibody (clone 4G9), anti-human
€435.00
In stock
SKU
AC-AT2499a
Catalog Number: AC-AT2499a
Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IF, E
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Size: 100 µg
Isotype: mouse IgG1 Kappa
Applications: WB, IHC, IF, E
Request Information AC-AT2499a">Request Information
Background:
This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.
Other Names:
NF-kappa-B essential modulator, NEMO, FIP-3, IkB kinase-associated protein 1, IKKAP1, Inhibitor of nuclear factor kappa-B kinase subunit gamma, I-kappa-B kinase subunit gamma, IKK-gamma, IKKG, IkB kinase subunit gamma, NF-kappa-B essential modifier, IKBKG, FIP3, NEMO
Antigen Type:
Recombinant Protein
Gene Name: IKBKG (HGNC:5961)
Gene ID: 8517
NCBI Accession: NP_001093326.2;NP_001093327.1;NP_001138727.1;NP_003630.1
Primary Accession: Q9Y6K9
Other Accession: BC050612
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.
Other Names:
NF-kappa-B essential modulator, NEMO, FIP-3, IkB kinase-associated protein 1, IKKAP1, Inhibitor of nuclear factor kappa-B kinase subunit gamma, I-kappa-B kinase subunit gamma, IKK-gamma, IKKG, IkB kinase subunit gamma, NF-kappa-B essential modifier, IKBKG, FIP3, NEMO
Antigen Type:
Recombinant Protein
Gene Name: IKBKG (HGNC:5961)
Gene ID: 8517
NCBI Accession: NP_001093326.2;NP_001093327.1;NP_001138727.1;NP_003630.1
Primary Accession: Q9Y6K9
Other Accession: BC050612
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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