IKK alpha (Phospho Thr23) polyclonal antibody, anti-human, mouse, rat

Background:
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein| a component of a cytokine-activated protein complex that is an inhibitor of the essential transcription factor NF-kappa-B complex| phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway| thereby activating the transcription factor.

Research Area: Cancer, Cardiovascular, Cell biology, Signal transduction, Immunology

Synonyms: Inhibitor of nuclear factor kappa-B kinase subunit alpha, CHUK, IKKA, TCF16, Inhibitor of nuclear factor kappa-B kinase subunit alpha, I-kappa-B kinase alpha, IKK-A, IKK-alpha, IkBKA, IkappaB kinase, Conserved helix-loop-helix ubiquitous kinase, I-kappa-B kinase 1, IKK1, Nuclear factor NF-kappa-B

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year