IKK beta polyclonal, anti-human

Quantity: 100 µg

Background:
IKBKB(Inhibitor of Kappa Light Chain Gene Enhancer in B Cells, Kinase of, Beta), also known as IKKB or NFKBIKB, is a protein that in humans is encoded by the IKBKB gene. This gene is mapped to chromosome 8p12-p11 by FISH. It is found that mutations in IKK2 had a more pronounced effect upon NFKB activation than did comparable mutations in IKK1. The activity of various antiinflammatory agents on the IKK complex has been texted, it has been found that aspirin and sodium salicylate specifically inhibit IKK-beta activity in vitro and in vivo by binding to IKK-beta to reduce ATP binding.

Description:
Rabbit IgG polyclonal antibody for Inhibitor of nuclear factor kappa-B kinase subunit beta (IKBKB) detection. Tested with WB, IHC-P in Human.

Synonyms:
I kappa B kinase 2 antibody, I kappa B kinase beta antibody, I-kappa-B kinase 2 antibody, I-kappa-B-kinase beta antibody, IkBKB antibody, IKK 2 antibody, IKK B antibody, IKK beta antibody, IKK-B antibody, IKK-beta antibody, IKK2 antibody, IKKB antibody, IKKB_HUMAN antibody, IMD15 antibody, Inhibitor of kappa light chain gene enhancer in B cells antibody, Inhibitor of kappa light polypeptide gene enhancer in B cells antibody, Inhibitor of kappa light polypeptide gene enhancer in B cells kinase beta antibody, Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase beta antibody, Inhibitor of nuclear factor kappa B kinase beta subunit antibody, Inhibitor of nuclear factor kappa B kinase subunit beta antibody, Inhibitor of nuclear factor kappa-B kinase subunit beta antibody, MGC131801 antibody, NFKBIKB antibody, Nuclear factor NF kappa B inhibitor kinase beta antibody, Nuclear factor NF-kappa-B inhibitor kinase beta antibody, Nuclear factor of kappa light chain gene enhancer in B cells inhibitor antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human IKK beta recombinant protein (Position: E398-S756). Human IKK beta shares 91% and 90% amino acid (aa) sequences identity with mouse and rat IKK beta, respectively.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.