IKK beta polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
IKBKB(Inhibitor of Kappa Light Chain Gene Enhancer in B Cells, Kinase of, Beta), also known as IKKB or NFKBIKB, is a protein that in humans is encoded by the IKBKB gene. Shindo et al.(1998) mapped the IKBKB gene to chromosome 8p12-p11 by FISH. Mercurio et al.(1997) found that mutations in IKK2 had a more pronounced effect upon NFKB activation than did comparable mutations in IKK1. Yin et al.(1998) tested the activity of various antiinflammatory agents on the IKK complex. They demonstrated that aspirin and sodium salicylate specifically inhibit IKK-beta activity in vitro and in vivo by binding to IKK-beta to reduce ATP binding.

Description:
Rabbit IgG polyclonal antibody for Inhibitor of nuclear factor kappa-B kinase subunit beta (IKBKB) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
I kappa B kinase 2 antibody, I kappa B kinase beta antibody, I-kappa-B kinase 2 antibody, I-kappa-B-kinase beta antibody, IkBKB antibody, IKK 2 antibody, IKK B antibody, IKK beta antibody, IKK-B antibody, IKK-beta antibody, IKK2 antibody, IKKB antibody, IKKB_HUMAN antibody, Inhibitor of kappa light chain gene enhancer in B cells antibody, Inhibitor of kappa light polypeptide gene enhancer in B cells antibody, Inhibitor of kappa light polypeptide gene enhancer in B cells kinase beta antibody, Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase beta antibody, Inhibitor of nuclear factor kappa B kinase beta subunit antibody, Inhibitor of nuclear factor kappa B kinase subunit beta antibody, Inhibitor of nuclear factor kappa-B kinase subunit beta antibody, MGC131801 antibody, NFKBIKB antibody, Nuclear factor NF kappa B inhibitor kinase beta antibody, Nuclear factor NF-kappa-B inhibitor kinase beta antibody, Nuclear factor of kappa light chain gene enhancer in B cells inhibitor antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human IKK beta(588-604aa QEMVRLLLQAIQSFEKK), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.A synthetic peptide corresponding to a sequence at the C-terminus of human IKK beta(588-604aa QEMVRLLLQAIQSFEKK), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.