IKK gamma monoclonal, anti-human

IKK gamma monoclonal, anti-human

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In stock
SKU
AC-AM8110a
Catalog Number: AC-AM8110a
Size: 80 µl, 400 µl
Isotype: mouse mouse IgG1
Clone Name: 55AT986.5.78
Applications: WB
Datasheet

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Background:
This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

Other Names:
NF-kappa-B essential modulator, NEMO, FIP-3, IkB kinase-associated protein 1, IKKAP1, Inhibitor of nuclear factor kappa-B kinase subunit gamma, I-kappa-B kinase subunit gamma, IKK-gamma, IKKG, IkB kinase subunit gamma, NF-kappa-B essential modifier, IKBKG, FIP3, NEMO

Target/Specificity:
This IKK gamma antibody was raised using purified His-tagged recombinant full length human IKK gamma.

Antigen Type: Recombinant Protein

Gene Name: IKBKG (HGNC:5961)
Gene ID: 8517
Primary Accession: Q9Y6K9
NCBI Accession: NP_001093326.2;NP_001093327.1;NP_001138727.1;NP_003630.1
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
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