IKK gamma (Phospho Ser85) polyclonal antibody, anti-human, mouse, rat

Background:
This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex| which activates NF-kappaB resulting in activation of genes involved in inflammation| immunity| cell survival| and other pathways. Mutations in this gene result in incontinentia pigmenti| hypohidrotic ectodermal dysplasia| and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

Research Area: Cancer, Cardiovascular, Cell biology, Immunology, Signal transduction, Epigenetics and nuclear signaling

Synonyms: NF-kappa-B essential modulator, IKBKG, FIP3, NEMO, NF-kappa-B essential modulator, NEMO, FIP-3, IkB kinase-associated protein 1, IKKAP1, Inhibitor of nuclear factor kappa-B kinase subunit gamma, I-kappa-B kinase subunit gamma, IKK-gamma, IKKG, IkB kinase subunit gamma, NF

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year