IKKalpha/IKK-1 polyclonal, anti-human antibody
€275.00
In stock
SKU
AC-ABV10151-100
Catalog Number: AC-ABV10151-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, IP
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB, IP
Datasheet
Request Information
Background:
IKKα (IkB kinase-α or IKK-1) is part of a large protein complex responsible for the inducible phosphorylation of IkB proteins. Human IKK-α is an 85 kDa peptide that has been shown to activate NFkB by phosphorylation of IkB proteins. IKKα interacts with its upstream kinase, NIK, and its downstream substrate, the IkB proteins. Mutations of IKKα in its kinase domain lead to a dominant-negative phenotype that suppresses TNF-α and IL-1β induced NFkB activation.
Other Names:
IKK-alpha, IKKA, IKK-A, IKBKA, NFKBIKA, TCF16, CHUK, IKK1
Primary Accession: O15111
Other Accession: NP_001269
Gene Name: CHUK
Gene ID: 1147
Concentration (mg/ml): 0.5 mg/ml
IKKα (IkB kinase-α or IKK-1) is part of a large protein complex responsible for the inducible phosphorylation of IkB proteins. Human IKK-α is an 85 kDa peptide that has been shown to activate NFkB by phosphorylation of IkB proteins. IKKα interacts with its upstream kinase, NIK, and its downstream substrate, the IkB proteins. Mutations of IKKα in its kinase domain lead to a dominant-negative phenotype that suppresses TNF-α and IL-1β induced NFkB activation.
Other Names:
IKK-alpha, IKKA, IKK-A, IKBKA, NFKBIKA, TCF16, CHUK, IKK1
Primary Accession: O15111
Other Accession: NP_001269
Gene Name: CHUK
Gene ID: 1147
Concentration (mg/ml): 0.5 mg/ml
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