IKZF3 Antibody (Center) Blocking peptide

Background:
This gene encodes a member of the Ikaros family ofzinc-finger proteins. Three members of this protein family (Ikaros,Aiolos and Helios) are hematopoietic-specific transcription factorsinvolved in the regulation of lymphocyte development. This geneproduct is a transcription factor that is important in theregulation of B lymphocyte proliferation and differentiation. BothIkaros and Aiolos can participate in chromatin remodeling.Regulation of gene expression in B lymphocytes by Aiolos is complexas it appears to require the sequential formation of Ikaroshomodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Atleast six alternative transcripts encoding different isoforms havebeen described.

Other Names:
Zinc finger protein Aiolos, Ikaros family zinc finger protein 3, IKZF3, ZNFN1A3

Gene Name: IKZF3

Gene ID: 22806
Primary Accession: Q9UKT9
Other Accession: NP_036613.2
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.