IL-1 beta polyclonal, anti-rat

IL-1 beta polyclonal, anti-rat

€455.00
In stock
SKU
AC-ABO12292
Catalog Number: AC-ABO12292
Size: 100 µg
Isotype: Rabbit IgG
Applications: E
Datasheet
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Description: "Rabbit IgG polyclonal antibody for Interleukin-1 beta(IL1B) detection. Tested with ELISA in Rat.
Protein Name: Interleukin-1 beta

Protein Function:
Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

Other Names: Interleukin-1 beta, IL-1 beta, Il1b

Subcellular Localization: Secreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of rat IL-1 beta (202-229aa DPKQYPKKKMEKRFVFNKIEVKTKVEFE), different from the related human sequence by five amino acids, and from the related mouse sequence by one amino acid.

Calculated MW: 30644

Purification: Immunogen affinity purified.

Format: Lyophilized

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Concentration (mg/ml): Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
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