IL-17A polyclonal, anti-human antibody
€275.00
In stock
SKU
AC-ABV10833-50
Catalog Number: AC-ABV10833-50
Size: 50 µg
Host: Rabbit IgG
Applications: WB, IHC, E
Datasheet
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Size: 50 µg
Host: Rabbit IgG
Applications: WB, IHC, E
Datasheet
Request Information
Background:
The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells.
Other Names:
CTLA-8, IL-17, IL-17A, Cytotoxic T-lymphocyte associated antigen 8
Primary Accession: Q16552
Gene Name: IL17A
Gene ID: 3605
The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells.
Other Names:
CTLA-8, IL-17, IL-17A, Cytotoxic T-lymphocyte associated antigen 8
Primary Accession: Q16552
Gene Name: IL17A
Gene ID: 3605
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