IL-18 polyclonal, anti-human, mouse, rat

Protein Family: Cytokines

Pathway and Disease: Signaling Molecules and Interaction, Immune System, Infectious Diseases

Description:
Interleukin-18 (IL-18) is a secreted cytokine that augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. IL-18 works by binding to the interleukin-18 receptor, and together with IL-12 it induces cell-mediated immunity following infection with microbial products like lipopolysaccharide (LPS).

Alternate Names: IL-18, IGIF, Interleukin-18, Interferon-gamma-inducing factor, IFN-gamma-inducing factor, Interleukin-1 gamma, IL-1 gamma, Iboctadekin, IL18, IL1F4

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P70380

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse IL-18.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.