IL-1α polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS6919
Background:
Two forms of interleukin-1, designated IL-1α and IL-1β, have been described. Although encoded by distinct genes and exhibiting roughly only 25% sequence identity, IL-1α and IL-1β bind to the same receptor and seem to elicit similar biological responses. IL-1 production is generally thought to be associated with inflammation, but it has also been shown to be expressed during kidney development, thymocyte differentiation and cartilage degradation. IL-1 plays a critical role in the regulation of immune response and inflammation, acting as an activator of T and B lymphocytes and natural killer (NK) cells.
Alternative Name:
Interleukin-1 alpha, IL-1 alpha, Hematopoietin-1, IL1A, IL1F1
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: IL-1α polyclonal antibody detects endogenous levels of IL-1α protein.
Immunogen:
Recombinant full length Human IL-1α.
MW: ~ 17 kDa
Swis Prot.: P01583
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Two forms of interleukin-1, designated IL-1α and IL-1β, have been described. Although encoded by distinct genes and exhibiting roughly only 25% sequence identity, IL-1α and IL-1β bind to the same receptor and seem to elicit similar biological responses. IL-1 production is generally thought to be associated with inflammation, but it has also been shown to be expressed during kidney development, thymocyte differentiation and cartilage degradation. IL-1 plays a critical role in the regulation of immune response and inflammation, acting as an activator of T and B lymphocytes and natural killer (NK) cells.
Alternative Name:
Interleukin-1 alpha, IL-1 alpha, Hematopoietin-1, IL1A, IL1F1
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: IL-1α polyclonal antibody detects endogenous levels of IL-1α protein.
Immunogen:
Recombinant full length Human IL-1α.
MW: ~ 17 kDa
Swis Prot.: P01583
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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