IL-1β Polyclonal Antibody

IL-1β Polyclonal Antibody

€0.00
In stock
SKU
ELK-ES2610
Catalog Number: ELK-ES2610
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-p, ELISA
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Background:
interleukin 1 beta(IL1B) Homo sapiens The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008],

Alternative Names:
IL1B, IL1F2, Interleukin-1 beta, IL-1 beta, Catabolin

Immunogen: The antiserum was produced against synthesized peptide derived from human IL-1beta. AA range:113-162

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 31

GeneID: IL1B

Storage: -20°C/1 year

NOTE: For Research Use Only
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