IL-1R2 Functional recombinant mAb (clone Praxy-1-1), anti-mouse
€385.00
In stock
SKU
AC-ADP0040-U0100
Catalog Number: AC-ADP0040-U0100
Size: 100 µg
Isotype: Mouse IgG2b
Applications: FC, E
Datasheet
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Size: 100 µg
Isotype: Mouse IgG2b
Applications: FC, E
Datasheet
Request Information
Background:
The inflammatory actions of IL-1α and -β- depend on their interaction with its receptor, IL-1R1, and can be negatively controlled by several inhibitors such as IL-1Ra, IL-1R type 2 (IL-1R2), SIGIRR and the soluble form of IL-1 receptor accessory protein (IL-1RAcP). IL-1R2 neutralizes IL-1 either as a surface decoy receptor or in a cleaved and secreted form. IL-1R2 is expressed on B cells, on neutrophils and on in vitro expanded human Tregs.
Other Names:
CD121 Antigen-like Family Member B; IL-1 Type II Receptor; Interleukin-1 Receptor β Interleukin-1 Receptor Type II; CD121b
Gene Name: Il1r2
Gene ID: 16178
Primary Accession: P27931
The inflammatory actions of IL-1α and -β- depend on their interaction with its receptor, IL-1R1, and can be negatively controlled by several inhibitors such as IL-1Ra, IL-1R type 2 (IL-1R2), SIGIRR and the soluble form of IL-1 receptor accessory protein (IL-1RAcP). IL-1R2 neutralizes IL-1 either as a surface decoy receptor or in a cleaved and secreted form. IL-1R2 is expressed on B cells, on neutrophils and on in vitro expanded human Tregs.
Other Names:
CD121 Antigen-like Family Member B; IL-1 Type II Receptor; Interleukin-1 Receptor β Interleukin-1 Receptor Type II; CD121b
Gene Name: Il1r2
Gene ID: 16178
Primary Accession: P27931
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