IL-2 (Rodent) polyclonal, anti-mouse, rat

Protein Family: Cytokines

Pathway and Disease: Signaling Molecules and Interaction, Immune System, Metabolic Disorders, Cancers

Description:
Interleukin-2 (IL-2) is produced by T-cells in response to antigenic or mitogenic stimulation. IL-2 is required for T-cell proliferation and other activities crucial to regulation of the immune response. IL-2 also stimulates B-cells, monocytes, lymphokine-activated killer cells, NK cells and glioma cells. T-cell acute lymphoblastic leukemia (T-ALL) is caused by a chromosomal abberation in IL-2 gene. IL-2 (Proleukin, Chiron) is used as a treatment for patients with renal cell carcinoma and metastatic melanoma. This antibody recognizes and neutralizes mouse and rat interleukin-2.

Alternate Names: interleukin-2, IL-2, T-cell growth factor, TCGF, IL2

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P04351

Antigen: Recombinant mouse IL-2

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.