IL-4R polyclonal, anti-human

Background:
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

Synonyms: CD124, IL4-BP, IL4RA

Cellular Location: Cell membrane Secreted

Immunogen:
A synthetic peptide of human IL-4R

Gene Symbol: IL-4R

Gene ID: 3566

Swiss prot: P24394

Calculated MW: 90kDa

Recommended dilution:
IHC 1:25-100

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.