IL-6R alpha polyclonal, anti-human
€295.00
In stock
SKU
K106877P
Catalog Number: K106877P
Size: 100 μl
Other size: 50 μl
Isotype: RabbitIgG
Applications: WB
Request Manual
Questions? Contact us!
Size: 100 μl
Other size: 50 μl
Isotype: RabbitIgG
Applications: WB
Request Manual
Questions? Contact us!
Background:
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
Synonyms: IL6R, CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80, interleukin 6 receptor
Cellular Location: Cell membrane Secreted
Immunogen:
A synthetic peptide of human IL-6R alpha
Gene Symbol: IL-6R alpha
Gene ID: 16194
Swiss prot: P08887
Calculated MW: 52kDa
Recommended dilution:
WB 1:500-2000
Purity:
Affinity purification
Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
Synonyms: IL6R, CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80, interleukin 6 receptor
Cellular Location: Cell membrane Secreted
Immunogen:
A synthetic peptide of human IL-6R alpha
Gene Symbol: IL-6R alpha
Gene ID: 16194
Swiss prot: P08887
Calculated MW: 52kDa
Recommended dilution:
WB 1:500-2000
Purity:
Affinity purification
Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
Storage:
Store at -20℃. Avoid freeze / thaw cycles.
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