IL10 Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP9112c
Background:
The protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
Other Names:
Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF, IL10
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP9112c was selected from the Center region of human IL10. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: IL10
Gene ID: 3586
Primary Accession: P22301
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
Other Names:
Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF, IL10
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP9112c was selected from the Center region of human IL10. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: IL10
Gene ID: 3586
Primary Accession: P22301
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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