IL10RA polyclonal, anti-human

Background:
The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

Synonyms: CD210, IL10R, CD210a, CDW210A, HIL-10R, IL-10R1

Cellular Location: Cytoplasm Membrane

Immunogen:
Recombinant protein of human IL10RA

Gene Symbol: IL10RA

Gene ID: 3587

Swiss prot: Q13651

Calculated MW: 63kDa

Recommended dilution:
IHC 1:50-200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.