IL11 polyclonal (N-Term), anti-human

IL11 polyclonal (N-Term), anti-human

€0.00
In stock
SKU
AC-AP22261a
Catalog Number: AC-AP22261a
Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB56890
Applications: WB, FC
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Background:
Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.

Other Names:
Interleukin-11, IL-11, Adipogenesis inhibitory factor, AGIF, Oprelvekin, IL11

Target/Specificity:
This IL11 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 27-61 amino acids from human IL11.

Antigen Type: Synthesized Peptide

Gene Name: IL11 (HGNC:5966)
Gene ID: 3589
Primary Accession: P20809
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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