IL12_2 polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP10687b
Catalog Number: AC-AP10687b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB28530
Applications: IHC-P, WB, FC
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB28530
Applications: IHC-P, WB, FC
Datasheet
Request Information
Background:
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.
Other Names:
Interleukin-12 receptor subunit beta-2, IL-12 receptor subunit beta-2, IL-12R subunit beta-2, IL-12R-beta-2, IL-12RB2, IL12RB2
Target/Specificity:
This IL12_2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 756-783 amino acids from the C-terminal region of human IL12_2.
Antigen Region:
756-783
Antigen Type: Synthetic Peptide
Gene Name: IL12RB2
Gene ID: 3595
Primary Accession: Q99665
NCBI Accession: NP_001245143.1;NP_001245144.1;NP_001245145.1;NP_001550.1
Other Accession: NP_001550.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.
Other Names:
Interleukin-12 receptor subunit beta-2, IL-12 receptor subunit beta-2, IL-12R subunit beta-2, IL-12R-beta-2, IL-12RB2, IL12RB2
Target/Specificity:
This IL12_2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 756-783 amino acids from the C-terminal region of human IL12_2.
Antigen Region:
756-783
Antigen Type: Synthetic Peptide
Gene Name: IL12RB2
Gene ID: 3595
Primary Accession: Q99665
NCBI Accession: NP_001245143.1;NP_001245144.1;NP_001245145.1;NP_001550.1
Other Accession: NP_001550.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review