IL12RB2 Polyclonal Antibody

Background:
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation.

Research Area: Cancer, Immunology

Synonyms:
I12R2, IL-12 receptor subunit beta-2, IL-12R subunit beta-2, IL-12R-beta-2, IL-12RB2, IL12 receptor beta 2, IL12R beta2, IL12RB2, Interleukin 12 receptor beta 2, Interleukin 12 receptor beta 2 chain, Interleukin-12 receptor subunit beta-2, RP11 102M16.1

Immunogen: Synthetic peptide of human IL12RB2

Swissprot: Q99665
Gene Accession: NP_001550

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-18648