IL13 antibody (clone 3H7), anti-human
€435.00
In stock
SKU
AC-AT2502a
Catalog Number: AC-AT2502a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: WB, IHC
Request Information AC-AT2502a">Request Information
Background:
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq]
Other Names:
Interleukin-13, IL-13, IL13, NC30
Antigen Type:
Recombinant Protein
Gene Name: IL13
Gene ID: 3596
NCBI Accession: NP_002179.2
Primary Accession: P35225
Other Accession: ALRH,BHR1,IL-13,MGC116786,MGC116788,MGC116789,P600
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq]
Other Names:
Interleukin-13, IL-13, IL13, NC30
Antigen Type:
Recombinant Protein
Gene Name: IL13
Gene ID: 3596
NCBI Accession: NP_002179.2
Primary Accession: P35225
Other Accession: ALRH,BHR1,IL-13,MGC116786,MGC116788,MGC116789,P600
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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