IL13 polyclonal (C-term), anti-human

IL13 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP13737b
Catalog Number: AC-AP13737b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33718
Applications: IHC-P, IF, WB
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Background:
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq].

Other Names:
Interleukin-13, IL-13, IL13, NC30

Target/Specificity:
This IL13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-146 amino acids from the C-terminal region of human IL13.

Antigen Region:
118-146

Antigen Type: Synthetic Peptide

Gene Name: IL13
Gene ID: 3596
Primary Accession: P35225
NCBI Accession: NP_002179.2
Other Accession: NP_002179.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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