IL15RA polyclonal (Center), anti-human
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In stock
SKU
AC-AP18818c
Catalog Number: AC-AP18818c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB39373
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB39373
Applications: WB
Datasheet
Request Information
Background:
This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.
Other Names:
Interleukin-15 receptor subunit alpha, IL-15 receptor subunit alpha, IL-15R-alpha, IL-15RA, CD215, Soluble interleukin-15 receptor subunit alpha, sIL-15 receptor subunit alpha, sIL-15R-alpha, sIL-15RA, IL15RA
Target/Specificity:
This IL15RA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-106 amino acids from the Central region of human IL15RA.
Antigen Region:
79-106
Antigen Type: Synthetic Peptide
Gene Name: IL15RA
Gene ID: 3601
Primary Accession: Q13261
NCBI Accession: NP_001230468.1;NP_001243694.1;NP_002180.1;NP_751950.2
Other Accession: NP_751950.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.
Other Names:
Interleukin-15 receptor subunit alpha, IL-15 receptor subunit alpha, IL-15R-alpha, IL-15RA, CD215, Soluble interleukin-15 receptor subunit alpha, sIL-15 receptor subunit alpha, sIL-15R-alpha, sIL-15RA, IL15RA
Target/Specificity:
This IL15RA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-106 amino acids from the Central region of human IL15RA.
Antigen Region:
79-106
Antigen Type: Synthetic Peptide
Gene Name: IL15RA
Gene ID: 3601
Primary Accession: Q13261
NCBI Accession: NP_001230468.1;NP_001243694.1;NP_002180.1;NP_751950.2
Other Accession: NP_751950.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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