IL16 Polyclonal Antibody

Background:
The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.

Research Area: Cancer, Immunology

Synonyms:
IL16, LCF, NIL16, PRIL16, prIL-16

Immunogen: Recombinant fusion protein of human IL16 (NP_757366.2).

Swissprot: Q14005
Gene ID: 3603

Calculated MW: 59 kDa/66 kDa/141 kDa
Observed MW: 122 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.