IL17RA polyclonal, anti-human, mouse, rat

Background:
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.

Synonyms: CANDF5, CD217, CDw217, IL-17RA, IL17R, IMD51, hIL-17R

Cellular Location: Membrane Secreted Single-pass type I membrane protein

Immunogen:
Recombinant protein of human IL17RA

Gene Symbol: IL17RA

Gene ID: 23765

Swiss prot: Q96F46

Calculated MW: 96kDa

Recommended dilution:
WB 1:1000-4000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.