IL18 binding protein (clone 5C7-D2-G4-B6), anti-human

Background:
The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine,IL18. It binds IL18,prevents the binding of IL18 to its receptor,and thus inhibits IL18-induced IFN-gamma production,resulting in reduced T-helper type 1 immune responses.This protein is constitutively expressed and secreted in mononuclear cells.Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease.Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq,Feb 2011]

Synonyms: IL18BPa

Cellular Location: Secreted

Immunogen:
Purified recombinant human IL18 binding protein protein fragments expressed in E.coli.

Gene Symbol: IL18 binding protein

Gene ID: 10068

Swiss prot: O95998

Calculated MW: 37kDa

Recommended dilution:
WB 1:400

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.