IL18 polyclonal, anti-human

Background:
A proinflammatory cytokine primarily involved in polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses (Probable). Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells.

Synonyms: IGIF, IL-18, IL-1g, IL1F4

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human IL18

Gene Symbol: IL18

Gene ID: 3606

Swiss prot: Q14116

Calculated MW: 22kDa

Recommended dilution:
WB 1:2000-5000, IHC 1:100-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.