IL18BP antibody (clone 2A9), anti-human
€435.00
In stock
SKU
AC-AT2507a
Catalog Number: AC-AT2507a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, E
Request Information AC-AT2507a">Request Information
Background:
The protein encoded by this gene is an inhibitor of the proinflammatory cytokine IL18. This protein binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. This protein is constitutively expressed and secreted in mononuclear cells. The expression of this protein can be enhanced by IFN-gamma. An elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternative splicing results in multiple transcript variants.
Other Names:
Interleukin-18-binding protein, IL-18BP, Tadekinig-alfa, IL18BP
Antigen Type:
Recombinant Protein
Gene Name: IL18BP
Gene ID: 10068
NCBI Accession: NP_001034748.1;NP_001034749.1;NP_001138527.1;NP_001138529.1;NP_005690.2;NP_766630.2;NP_766632.2
Primary Accession: O95998
Other Accession: BC044215
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is an inhibitor of the proinflammatory cytokine IL18. This protein binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. This protein is constitutively expressed and secreted in mononuclear cells. The expression of this protein can be enhanced by IFN-gamma. An elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternative splicing results in multiple transcript variants.
Other Names:
Interleukin-18-binding protein, IL-18BP, Tadekinig-alfa, IL18BP
Antigen Type:
Recombinant Protein
Gene Name: IL18BP
Gene ID: 10068
NCBI Accession: NP_001034748.1;NP_001034749.1;NP_001138527.1;NP_001138529.1;NP_005690.2;NP_766630.2;NP_766632.2
Primary Accession: O95998
Other Accession: BC044215
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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