IL1B Antibody (Center) Blocking Peptide
€363.00
In stock
SKU
AC-BP8531c
Background:
IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity.
Other Names:
Interleukin-1 beta, IL-1 beta, Catabolin, IL1B, IL1F2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8531c was selected from the Center region of human IL1B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: IL1B (HGNC:5992)
Gene ID: 3553
Primary Accession: P01584
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity.
Other Names:
Interleukin-1 beta, IL-1 beta, Catabolin, IL1B, IL1F2
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP8531c was selected from the Center region of human IL1B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: IL1B (HGNC:5992)
Gene ID: 3553
Primary Accession: P01584
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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