IL1B antibody (clone 2A8), anti-human
€435.00
In stock
SKU
AC-AT2509a
Catalog Number: AC-AT2509a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IF, IP, E
Request Information AC-AT2509a">Request Information
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, IF, IP, E
Request Information AC-AT2509a">Request Information
Background:
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Other Names:
Interleukin-1 beta, IL-1 beta, Catabolin, IL1B, IL1F2
Antigen Type:
Recombinant Protein
Gene Name: IL1B (HGNC:5992)
Gene ID: 3553
NCBI Accession: NP_000567.1
Primary Accession: P01584
Other Accession: BC008678
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Other Names:
Interleukin-1 beta, IL-1 beta, Catabolin, IL1B, IL1F2
Antigen Type:
Recombinant Protein
Gene Name: IL1B (HGNC:5992)
Gene ID: 3553
NCBI Accession: NP_000567.1
Primary Accession: P01584
Other Accession: BC008678
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
| Is Featured? | No |
|---|
Write Your Own Review