IL1B monoclonal (Center) (Ascites), anti-human
€470.00
In stock
SKU
AC-AM2121a
Catalog Number: AC-AM2121a
Size: 100 µl
Isotype: mouse IgG1
Clone Name: 614CT4.3.1
Applications: WB
Datasheet
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Size: 100 µl
Isotype: mouse IgG1
Clone Name: 614CT4.3.1
Applications: WB
Datasheet
Request Information
Background:
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq].
Other Names:
Interleukin-1 beta, IL-1 beta, Catabolin, IL1B, IL1F2
Target/Specificity:
This IL1B antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 148-174 amino acids from the Central region of human IL1B.
Antigen Region:
148-174
Antigen Type: Synthetic Peptide
Gene Name: IL1B (HGNC:5992)
Gene ID: 3553
Primary Accession: P01584
NCBI Accession: NP_000567.1
Other Accession: P14628; P79182; NP_000567.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq].
Other Names:
Interleukin-1 beta, IL-1 beta, Catabolin, IL1B, IL1F2
Target/Specificity:
This IL1B antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 148-174 amino acids from the Central region of human IL1B.
Antigen Region:
148-174
Antigen Type: Synthetic Peptide
Gene Name: IL1B (HGNC:5992)
Gene ID: 3553
Primary Accession: P01584
NCBI Accession: NP_000567.1
Other Accession: P14628; P79182; NP_000567.1
Format: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
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