IL1B polyclonal (Center), anti-human, mouse
€0.00
In stock
SKU
AC-AP8531C
Catalog Number: AC-AP8531C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB21917
Applications: IHC-P, WB, FC
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB21917
Applications: IHC-P, WB, FC
Datasheet
Request Information
Background:
IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity.
Other Names:
Interleukin-1 beta, IL-1 beta, Catabolin, IL1B, IL1F2
Target/Specificity:
This IL1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-174 amino acids of human IL1B.
Antigen Region:
148-174
Antigen Type: Synthetic Peptide
Gene Name: IL1B (HGNC:5992)
Gene ID: 3553
Primary Accession: P01584
NCBI Accession: NP_000567.1
Other Accession: P14628; P79182
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity.
Other Names:
Interleukin-1 beta, IL-1 beta, Catabolin, IL1B, IL1F2
Target/Specificity:
This IL1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-174 amino acids of human IL1B.
Antigen Region:
148-174
Antigen Type: Synthetic Peptide
Gene Name: IL1B (HGNC:5992)
Gene ID: 3553
Primary Accession: P01584
NCBI Accession: NP_000567.1
Other Accession: P14628; P79182
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review