IL1RAP Polyclonal Antibody

Background:
Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection, tissue damage, or stress, by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms, one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.

Research Area: Immunology, Cardiovascular

Synonyms:
C3orf13, FLJ37788, IL 1 receptor accessory protein, IL 1R3, IL 1RAcP, IL 1RAP, Interleukin 1 Accessory Protein, interleukin 1 receptor 3, Interleukin 1 receptor accessory protein

Immunogen: Recombinant Human Interleukin-1 receptor accessory protein

Swissprot: Q9NPH3
Gene ID: 3556

Purification Method: Antigen Affinity Purification

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.

Concentration: 0.7mg/mL
Dilution: IHC 1:100-1:300

Storage:
Store at -20℃. Avoid freeze / thaw cycles.